Cisco will be supporting Exchange 2010 for Unity. Here is the timeline :
Cisco Unity 7.0 – March 31, 2010
Cisco Unity 5.0 – May 31, 2010
Cisco Unity 8.0 – June 30, 2010
An Engineering Special (ES) build will be available for download as validation is completed for each release of Cisco Unity. If you are running anything pre-Unity 5.0, and who plan to upgrade to Exchange 2010, you should upgrade to Cisco Unity 7.0 first, once they have the ES available, before you do an upgrade to Exchange 2010.